Summary
About the Role
Key Responsibilities:
Lead matrix-oriented platform teams for the development of siRNA therapeutics
Experience with end-to-end NGS experiments including library preparation, sequencing, and analysis
Drive innovation based on data mining form hypothesis generation to conduct studies in a collaborative environment across Biomedical Research
Design, plan and supervise siRNA cell-based screening activities
Perform novel assay development and optimization for cell-based assays with a focus on improving throughput with automation
With supervision lead junior scientists in the lab and with data analysis
Represent xRNA team on cross-functional project teams to advance siRNA programs through the development pipeline
Document experiments in lab notebook, conduct data analysis, interpretation and present findings to team in a timely manner
Role Requirements:
PhD in biochemistry or biology or related scientific discipline
3 - 5 years of post-PhD research experience gained in academia as a Postdoc and/or in industry
Research experience in siRNA biology. Knowledge of siRNA therapeutics would be an advantage.
Strong genomics background with expertise in RNA-Seq from experiment to data processing
Able to run R scripts independently
Expertise in mammalian cell culture from immortalized to primary cells
Experience with cross functional teams and ability to serve as a point of contact for the team with minimal supervision
Strong multi-tasking, organizational, attention to detail, verbal/written communication skills
Ability to collaborate and thrive in fast-paced, team-oriented environment
Desired Requirements:
Expertise with BioMek or Opentrons liquid handlers
Proficient in R and/or Python. Machine Learning experience a plus.
*Restrictions on working flexibility may apply to this position and can be discussed at interview as required
Accessibility and accommodation
Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
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