Novartis is committed to supporting education about biomarker testing and precision medicine, to equip healthcare professionals with the knowledge and ability to provide patients with the best possible care. Digital and video resources are available on biomarker testing for solid tumors and hematology, as well as a comprehensive precision medicine digital binder.

Precision Medicine 101 

These resources provide an overview of key concepts around precision medicine as well as principles of biomarker testing and personalized therapies. Topics related to improving biomarker test availability are also covered.

Diagnostic Challenges in Precision Medicine 

This resource explores the diagnostic challenges in Precision Medicine for patients who have started on targeted therapy. 
Download Diagnostic Challenges in Precision Medicine (PDF 0.14 MB)

Molecular Diagnostics in Personalized Cancer Care

This resource provides an overview of precision oncology, the role of the multidisciplinary team (MDT), biomarker testing methods, and considerations for sample collection.
Download the Molecular Diagnostics in Personalized Cancer Care Brochure (PDF 1.0 MB)

Essential Elements of Biomarker Testing

This resource provides an overview of the essential elements of biomarker testing during the diagnostic journey.
Download the Essential Elements of Biomarker Testing During the Diagnostic Journey Brochure (PDF 1.3 MB)

Biomarker Testing Reimbursement

This resource reviews the 14-day rule and the biomarker tests that may be exempt from this policy. 
Download the Biomarker Testing Reimbursement Brochure (PDF 0.8 MB)

Molecular Profiling in Common Cancers

This resource reviews key information on frequently used molecular profiling assays. 
Download the Molecular Profiling in Common Cancers Brochure (PDF 1.0 MB)

The Ins and Outs of Test Requisition Forms

This resource provides an overview of the importance of test requisition forms and pathology reports, including potential considerations for formatting and layout.
Download the Ins and Outs of Test Requisition Forms Brochure (PDF 1.0 MB)

Identifying Potential Challenges During the Diagnostic Journey

This resource explores identifying potential challenges during the diagnostic journey.
Download the Identifying Potential Challenges During the Diagnostic Journey Brochure (PDF 2.2 MB)

Clinical Practice Gaps Affecting Precision Oncology

This resource explores clinical practice gaps affecting precision oncology.
Download the Clinical Practice Gaps Affecting Precision Oncology Brochure (PDF 1.3 MB)
 

Solid Tumors

These resources provide a detailed overview of biomarker testing approaches and the importance of biomarker testing in select common solid tumors.

Early Breast Cancer Risk of Recurrence Profile

This resource is a brief handout providing an overview of early breast cancer (eBC) risk of recurrence, individualized risk assessment, and practical considerations for patient management to decrease risk in HR+/HER2- eBC. 
Download the Early Breast Cancer Risk of Recurrence Profile (PDF 0.25 MB)

Individualize the Risk of Recurrence in Early Breast Cancer

This resource provides an overview of the risk of recurrence in HR+ eBC, the importance of appropriate risk assessments in HR+/HER2- eBC, and considerations to further individualize risk assessment by combining complementary prognostic information.
Download the Individualize the Risk of Recurrence in Early Breast Cancer Brochure (PDF 3.6 MB)

Getting a Personalized Risk Assessment in Early Breast Cancer – A Patient Journey

This resource provides an overview of a hypothetical patient journey with early breast cancer (eBC), highlighting the important role the multidisciplinary team (MDT) plays when assessing risk, and clinical considerations for treatment decisions in HR+/HER2- eBC.
Download the Getting a Personalized Risk Assessment in Early Breast Cancer – A Patient Journey Case Study (PDF 1.0 MB)

Biomarker Testing in Metastatic Breast Cancer

This resource provides an overview of metastatic breast cancer (mBC), the role of the MDT in biomarker testing, and considerations for sample collection and biomarker testing in mBC.
Download the Biomarker Testing in Metastatic Breast Cancer Brochure (PDF 1.9 MB)

Biomarkers in Advanced and Metastatic Melanoma

This resource provides an overview of predictive and prognostic biomarkers in advanced or metastatic melanoma, as well as guideline recommendations for testing.
Download the Biomarkers in Advanced and Metastatic Melanoma Brochure (PDF 1.1 MB)

The Impact of Pan-Tumor Biomarker Testing

This resource provides an overview of pan-tumor biomarker testing and its importance in identifying therapy options for patients, including discussions of testing in select rare solid tumors, testing in neuro-oncology, and the utility of panel testing for pan-tumor biomarkers.
Download the Impact of Pan-Tumor Biomarker Testing Brochure (PDF 2.4 MB)

The Importance of a Molecular Diagnosis in Metastatic Non–Small Cell Lung Cancer (mNSCLC)

This resource provides an overview of biomarker testing in mNSCLC, the role of the MDT, testing with small samples, next-generation sequencing (NGS), and potential considerations to improve biomarker testing.
Download the Importance of a Molecular Diagnosis in mNSCLC Brochure (PDF 3.0 MB)

Hematology

These resources provide a detailed overview of biomarker testing approaches and challenges for hematologic disorders.

Biomarker Testing and Its Role in PNH 

This resource explores biomarker testing for patients with paroxysmal nocturnal hemoglobinuria (PNH). It provides relevant information on the role of biomarker testing with flow cytometry in diagnosing and monitoring PNH, the importance of routine monitoring, and additional PNH resources including a lab value tracker.

Download Biomarker Testing and Its Role in PNH (PDF 3.4 MB) 

Paroxysmal Nocturnal Hemoglobinuria Laboratory Contact Quick Reference List 

This resource provides a quick reference list for clinical laboratories offering flow cytometry testing along with a brief review of the importance of routing monitoring in PNH. 
Download the Paroxysmal Nocturnal Hemoglobinuria Laboratory Contact Quick Reference List (PDF 3.9 MB)

Paroxysmal Nocturnal Hemoglobinuria 1-Pager for Lab Values

This resource provides a quick reference for checking select lab values related to paroxysmal nocturnal hemoglobinuria (PNH) and a reminder of when to test patients using high-sensitivity flow cytometry.
Download the PNH Lab Values Flashcard (PDF 0.2 MB)

Identifying Paroxysmal Nocturnal Hemoglobinuria With Flow Cytometry

This resource enhances your understanding of PNH and its accurate diagnosis using flow cytometry.
Download the Identifying Paroxysmal Nocturnal Hemoglobinuria With Flow Cytometry Brochure (PDF 0.85 MB)

Understanding Challenges in Hematologic Diagnostics: Paroxysmal Nocturnal Hemoglobinuria

This resource provides a better understanding of the diagnostic challenges in patients with PNH.
Download the Understanding Challenges in Hematologic Diagnostics: Paroxysmal Nocturnal Hemoglobinuria Brochure (PDF 1.0 MB)

The Complement System for Paroxysmal Nocturnal Hemoglobinuria 

This resource provides a quick reference depicting the role of the complement system in PNH along with considerations for routine monitoring. 
Download the Complement System for Paroxysmal Nocturnal Hemoglobinuria 1-Pager (PDF 0.4 MB)

Biomarker Testing and Its Role in Your Early Breast Cancer Journey 

This resource explores biomarker testing for patients with early breast cancer. Find relevant information for each step of the diagnostic journey, including the discussion of risk of recurrence, germline genetic testing, and types of therapy available to early breast cancer patients. 
Download Biomarker Testing and Its Role in Your Early Breast Cancer Journey (PDF 2.0 MB)

Biomarker Testing and Its Role In Your Metastatic Breast Cancer Journey 

This resource explores biomarker testing for patients with metastatic breast cancer. Find relevant information for each step of the metastatic diagnostic journey, including the need for rebiopsy, the differences between tissue and liquid biopsies, the different actionable biomarkers, and types of therapy that are available to metastatic breast cancer patients. 
Download Biomarker Testing and Its Role In Your Metastatic Breast Cancer Journey (PDF 2.2 MB)

Biomarker Testing and Its Role in Your Metastatic Non–Small Cell Lung Cancer (NSCLC) Journey 

This resource explores biomarker testing for patients with mNSCLC. Find relevant information of the role of biomarker testing in mNSCLC, along with different types of biomarkers patients should be tested for, and types of therapy available to patients with mNSCLC. 
Download Biomarker Testing and Its Role in Your Metastatic Non–Small Cell Lung Cancer (NSCLC) Journey (PDF 2.7 MB)

Biomarker Testing and Its Role in Your Advanced and Metastatic Melanoma Journey 

This resource explores biomarker testing for patients with advanced or metastatic melanoma cancer. Find relevant information on the role of biomarker testing in advanced or metastatic melanoma, along with different types of biomarkers for which patients should be tested, and types of therapy available to patients with advanced or metastatic melanoma. 
Download Biomarker Testing and Its Role in Your Advanced and Metastatic Melanoma Journey (PDF 7.0 MB)

Biomarker Testing and Its Role in Your Metastatic Cancer Journey 

This resource explores biomarker testing for patients with metastatic cancer. It provides relevant information on the role of biomarker testing in metastatic cancer, an overview of different types of biomarkers for which patients should be tested, including pan-tumor biomarkers, differences between single-gene tests and multigene panels, and an overview of the types of therapies available to patients with metastatic cancer and actionable pan-tumor biomarkers.
Download Biomarker Testing and Its Role in Your Metastatic Cancer Journey (PDF 3.21 MB)

Biomarker Testing and Its Role in PNH 

This resource explores biomarker testing for patients with paroxysmal nocturnal hemoglobinuria (PNH). It provides relevant information on the role of biomarker testing with flow cytometry in diagnosing and monitoring PNH, the importance of routine monitoring, and additional PNH resources including a lab value tracker.
Download Biomarker Testing and Its Role in PNH (PDF 3.4 MB)